SNP3 polymorphism in apo A-V gene is associated with small dense LDL particles in Type 2 diabetes
نویسندگان
چکیده
منابع مشابه
Oxidized LDL is Correlated with Urine Albumin in Type 2 Diabetes Mellitus: A Case-Control Study
Objective: In patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. We designed a study for comparing the level of Ox-LDL in diabetic patients with Macro-albuminuria, Micro-albuminuria, versus Normo-albuminuric. Materials and Methods: One hundred and thirty five patients with type 2 dia...
متن کاملSmall dense LDL is more susceptible to glycation than more buoyant LDL in Type 2 diabetes.
Glycation of apoB (apolipoprotein B) of LDL (low-density lipoprotein) increases its atherogenicity. Concentrations of both serum glyc-apoB (glycated apoB) and SD-LDL (small dense LDL) (syn LDL3; D=1.044-1.063 g/ml) are increased in diabetes and are closely correlated. We studied whether SD-LDL is more susceptible to glycation in vitro than more buoyant LDL in statin- and non-statin-treated Type...
متن کاملStudy of Polymorphism Rs4612666 in NLRP3 Gene in Patients with Type 2 Diabetes in East Azerbaijan
Introduction: Type 2 diabetes is a common multifactorial disease. Studies have shown that the NLRP3 gene plays an important role in insulin resistance. The aim of this study was to investigate the association of rs4612666 polymorphisms of NLRp3 gene with type 2 diabetes in the population of East Azarbaijan province. Methods: In this case-control study, blood samples from 110 patients and 110 h...
متن کاملVitamin D Deficiency is Associated with the Metabolic Syndrome in Subjects with Type 2 Diabetes
Background and Objectives: There is convincing evidence that subjects concomitantly affected by type 2 diabetes (T2D) and metabolic syndrome (MeS) are at greater risk for cardiovascular disease (CVD). Many metabolic derangements in T2D might be attributed to poor vitamin D status. The purpose of this study was to investigate the associations among vitamin D status, MeS and glycemic status in su...
متن کاملAssociation of rs2274907 polymorphism of omentin gene with type 2 diabetes in Iranian population
Background: Diabetes is one of the most common chronic metabolic diseases in the world that is caused by decreased insulin secretion or insulin resistance and fat accumulation in visceral adipose tissue (IR). Omentin is a protein inferred from adipose tissue that is associated with the rate of diabetes. The aim of this study was to investigate the relationship between rs2274907 polymorphism of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Diabetologia
سال: 2004
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-003-1308-0